Paper 13381-43
Paper 13381-43
Light-based biofabrication and volumetric bioprinting technologies to engineer complex tissues and organoids (Invited Paper)
29 January 2025 • 2:00 PM - 2:30 PM PST | Moscone South, Room 155 (Upper Mezz)
Abstract
Using visible light volumetric bioprinting technologies and novel, protein-derived photoresponsive hydrogels, fragile complex mini-organ models, also termed organoids, can be safely assembled into centimeter scale living tissues in a matter of few seconds. Herein, the most recent advances in light-driven biofabrication will be presented, together with our efforts to engineer functional blood vessels, breast gland tissue, and pancreatic tissues as advanced biological models, using organoids as living building blocks. Novel volumetric light projection techniques will also be presented, highlighting how single photon projection technologies can enable advanced printing, biomolecules patterning, and imaging across large, anatomically relevant constructs.
Presenter
Riccardo Levato
Univ. Medical Ctr. Utrecht (Netherlands)
Riccardo Levato is Associate Professor of Translational Bioengineering and Biomaterials at the Department of Clinical Sciences (Utrecht University), and at the Department of Orthopaedics of the University Medical Center Utrecht. He is also Principal Investigator at the Regenerative Medicine Center Utrecht, where he coordinates a multidisciplinary team of engineers, materials scientists, chemist, physicists, and biologists (https://www.levatolab.eu/team), focusing on the development of novel 3D bioprinting and photonics technologies, biomaterials and cell engineering techniques to build in the lab tissues for regenerative medicine, and as advanced in vitro models for drug discovery, disease modelling, biomedical research, and as replacement of animal experimentation. He is an European Research Council laureate, and holds a Vidi grant (Dutch Research Council), and he received several awards from the European Society for Biomaterials, TERMIS, and International Society for Biofabrication