Paper 13354-8
Paper 13354-8
Laser bioprinting of cells bioinks for ex vivo graft fabrication (Invited Paper)
28 January 2025 • 2:35 PM - 3:00 PM PST | Moscone South, Room 201 (Level 2)
Abstract
Bioprinting, especially using Laser Induced Forward Transfer (LIFT), shows significant potential for creating living tissues by precisely printing cells and biomaterials. This technique fabricates structures that mimic native tissue functions, useful in regenerative medicine. In this study, various cell-laden bioinks were printed with LIFT, utilizing a Nd:YAG laser at 532nm to create ex vivo 3D structures. Detailed rheological characterization and optimized laser parameters ensured accurate cell depositions. Mouse-derived urothelial and smooth muscle cells were printed within biomaterials like Platelet Lysates methacrylated (PLMA) and hydrogels, forming a 3D bladder graft. LIFT bioprinting demonstrates significant advantages for controlled tissue fabrication.
Presenter
National Technical Univ. of Athens (Greece)
Ioanna Zergioti is a Professor at the NTUA, School of Applied Mathematics and Physical Sciences. After her PhD, she worked as a post-doctoral researcher in the Max Planck Institut für Biophysikalische Chemie in Göttingen, on Laser matter inter-actions studies. Then, she worked as a post-doctoral researcher at Philips CFT on Laser Sintering of sol gels for electronics until 2000. Her main activities are related to the laser printing of organic and inorganic materials on electronics and biomedical applications as well as laser bioprinting studies. She has co-authored more than 200 publications in international refereed journals and in conference proceedings. She has been involved in many Research projects funded by the EU and she co-inventor in 10 patents.