SILIOS Technologies

SILIOS Technologies is a French high-tech company located in Provence, in the south of France. It is specialized in micro-optical technologies. Over the past 15 years, SILIOS Technologies has developed the COLOR SHADES® technology, allowing the manufacturing of multi-spectral pixelated filters for the visible, NIR, and SWIR domains. Each cell of these filters can be sized at a scale down to 4.5 microns. With this long experience in functionalizing of focal plane arrays, SILIOS technologies recently undertook the development of custom wavefront imagers for microscopy, based on commercial CMOS sensors, and is now pleased to present, in World premiere at BIOS 2025, its off-the-shelf 20Mpix Wavefront imaging camera for live cell and tissue imaging: the TIKEI. The TIKEI WFI camera arrives on the market just right after the MAKATEA camera which was also showcased in World premiere at BIOS 2024 Based on a Quantitative Phase Imaging (QPI) Technique, the TIKEI and MAKATEA WFI cameras are capable of mapping both the intensity and phase of a light beam with a high spatial resolution and sensitivity making them suited for optical microscopy investigations, e.g. to characterize cells, micro and nano-objects for bio-imaging and nanophotonics applications. The TIKEI and MAKATEA WFI cameras are particularly valuable for single-cell dry mass measurements, from a single image acquisition. Indeed during its life, the dry mass of a cell, i.e., the mass of all cellular content except water, is deeply modified. These changes are related to all the metabolic and structural cell functions. The study of dry mass consequently provides crucial insights into cellular aspects, such as the cell cycle, the impact of stimuli or drugs, as well as cell metabolism. This knowledge proved valuable for studying individual cell or cell populations. You are welcome to visit SILIOS booth N° 8214 at the BIOS 2025 exhibition to view amazing cell images captured with TIKEI and MAKATEA, watch a short movie of dividing cells, and discover the TIKEI and MAKATEA WFI cameras themselves of course. We’ll be pleased to take this opportunity to discuss how both TIKEI and MAKATEA WFI cameras can enhance your applications in biology.