Paper 13305-20
Paper 13305-20
Wavenumber-space wavefront-sensorless adaptive-optics optical coherence tomography of the retina in vivo
27 January 2025 • 5:00 PM - 5:15 PM PST | Moscone South, Room 203 (Level 2)
Abstract
Adaptive-optics optical coherence tomography (AO-OCT) can resolve cellular-scale structures in the retina and their dynamics. However, the hardware and software complexity have restricted its spreading at research level and clinical translation. Wavefront sensorless (WS) AO-OCT profiles as an alternative with simplified hardware but software control is still complex as current paradigm require motion-free volume reconstruction at real-time achieved using GPU. We propose to drive the WSAO optimization with the spectral fringes modulation, eliminating the need for tomogram reconstruction and increasing the robustness against axial motion, and demonstrate the performance in human retina imaging with 11 Zernike modes correction in 1.4 s.
Presenter
Massachusetts General Hospital (United States)
Sebastián Ruiz-Lopera is a PhD student in the Electrical Engineering and Computer Science program at MIT. He received his Bachelor’s degree in Engineering Physics and Master’s degree in Applied Physics from EAFIT University (Colombia). He is currently focused on developing post-processing techniques for improving image quality and contrast in structural and functional OCT with standard systems and customized systems with adaptive-optics.