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25 - 30 January 2025
San Francisco, California, US
Conference 13305 > Paper 13305-1
Paper 13305-1

Large-area dynamic contrast MHz optical coherence tomography for label-free imaging of porcine tissue

27 January 2025 • 10:15 AM - 10:30 AM PST | Moscone South, Room 203 (Level 2)

Abstract

We demonstrate a 3.2MHz-OCT system for inter-volumetric dynamic optical coherence tomography of ex vivo porcine tissue. Employing a home-built Fourier Domain mode locking (FDML) laser with a 1310nm wavelength, the system achieved a lateral resolution of 1.74μm and a frame rate of 612Hz. A motorized XYZ positioning stage enabled the precise acquisition of multiple volumes, which were seamlessly stitched together to generate a comprehensive dataset with a total area of 2.6 × 2.6mm². Validations against histological sections confirmed the system’s ability to visualize cellular tissue structures.

Presenter

Univ. zu Lübeck (Germany)
Sazgar Burhan completed her master’s degree in medical engineering at the University of Luebeck in Germany. In December 2022, she became a PhD student in the research group of Prof. Robert Huber at the University of Luebeck.
Presenter/Author
Univ. zu Lübeck (Germany)
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Univ. zu Lübeck (Germany)
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Mario Pieper
Univ. zu Lübeck (Germany)
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Tjalfe Laedtke
Univ. zu Lübeck (Germany)
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Thorge Grahl
Univ. zu Lübeck (Germany)
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Medical Laser Center Lübeck GmbH (Germany)
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Massachusetts General Hospital (United States)
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Univ. zu Lübeck (Germany)
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Peter König
Univ. zu Lübeck (Germany)
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Univ. zu Lübeck (Germany)