Integrated intravaginal OCT/OCTA/OCE probe for quantitative measurements of the vagina tissue

We developed an integrated intravaginal OCT/OCTA/OCE probe to quantitatively assess vaginal tissue. This multifunctional probe combines optical coherence tomography, angiography, and elastography, enabling detailed analysis of blood vessel density, vaginal epithelium thickness, and tissue stiffness. Using an ex vivo vaginal sample, we demonstrated the probe's ability to provide comprehensive imaging and mechanical property measurements, offering valuable insights for optimizing laser-based treatments for genitourinary syndrome of menopause. This innovative approach could significantly enhance long-term treatment evaluation and improve the quality of life for affected women.