Photonics West Exhibition opens Tuesday
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25 - 30 January 2025
San Francisco, California, US
Conference 13305 > Paper 13305-40
Paper 13305-40

Analyzing the impact of speckle in PS-OCT data

28 January 2025 • 2:30 PM - 2:45 PM PST | Moscone South, Room 203 (Level 2)

Abstract

PS-OCT visualizes microstructure by measuring the pathlength difference, amplitude, and polarization states of backscattered light. Speckle causes noise-like effects in PS-OCT scans due to small scattering structures. We modeled the effect of speckle on PS-OCT scans and analyzed changes in the degree of polarization (DOP) and depth-resolved retardance throughout a birefringent medium. We also characterized the reduction of noise in PS-OCT data with Stokes vector filtering. Determining the underlying properties of PS-OCT data is an important step to developing future noise compensation and reduction methods for characterizing ground-truth data and improving scan interpretability.

Presenter

Maxina Sheft
Wellman Ctr. for Photomedicine (United States), Massachusetts Institute of Technology (United States)
Maxina Sheft is a PhD candidate in the department of Health Sciences and Technology at the Massachusetts Institute of Technology. She is supervised by Dr. Martin Villiger and Dr. Brett Bouma at the Wellman Center for Photomedicine. Her work is focused on studying polarization-sensitive optical coherence tomography (PS-OCT) and the use of optics in neuroimaging.
Presenter/Author
Maxina Sheft
Wellman Ctr. for Photomedicine (United States), Massachusetts Institute of Technology (United States)
Author
Georgia L. Jones
Wellman Ctr. for Photomedicine (United States), Massachusetts Institute of Technology (United States)
Author
National Taiwan Univ. (Taiwan)
Author
Wellman Ctr. for Photomedicine (United States), Massachusetts Institute of Technology (United States)
Author
Wellman Ctr. for Photomedicine (United States)
Author
Brett E. Bouma
Wellman Ctr. for Photomedicine (United States), Massachusetts Institute of Technology (United States)
Author
Wellman Ctr. for Photomedicine (United States)