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25 - 30 January 2025
San Francisco, California, US
Conference 13305 > Paper 13305-59
Paper 13305-59

A basis method for single-shot recovery of the combined confocal and fall-off function from multiple OCT A-scans

29 January 2025 • 11:15 AM - 11:30 AM PST | Moscone South, Room 203 (Level 2)

Abstract

We present a new single-shot method to extract the combined confocal and fall-off functions and remove system-generated depth-dependent effects from OCT images. This method requires no prior knowledge of the OCT system parameters or assumed form for the confocal and fall-off functions. Basis functions allow for greater degrees of freedom to model the combined function. Only two or more vertically shifted A-scans (or B-scans) of a sample are required for this method, which is validated with simulation and experimental data (three-layer PDMS/TiO2 phantom and human fingertip OCT images). Improvement over the standard ratio fit method is demonstrated.

Presenter

Daniel J. Phan
Vanderbilt Univ. (United States)
Daniel Phan is a third-year PhD student in the Department of Biomedical Engineering at Vanderbilt University. He received his Bachelor of Engineering in biomedical engineering at Dartmouth College in 2022. He is currently in Professor Audrey Bowden’s Lab at Vanderbilt working on visible light optical coherence tomography (OCT) for applications in low-resource settings. Current research topics include spectroscopic OCT, confocal function extraction, and attenuation coefficient estimation. He has a particular interest in working with children and helping those in need through his work. In his free time, Daniel likes to spend time outdoors with friends, cook delicious foods, make intricate origami, and watch movies.
Presenter/Author
Daniel J. Phan
Vanderbilt Univ. (United States)
Author
Vanderbilt Univ. Medical Ctr. (United States)
Author
Vanderbilt Univ. Medical Ctr. (United States)
Author
Vanderbilt Univ. (United States)