Technical Event
Panel Discussion: Is Light Dosimetry Necessary for Optimal PDT?
26 January 2025 • 9:00 AM - 10:30 AM PST | Moscone South, Room 151 (Upper Mezz)
Panel Moderator:
Lothar Lilge, Univ. Health Network (Canada)
Panelists:
Dominic Robinson, Erasmus MC (Netherlands)
Brian Pogue, Univ. of Wisconsin-Madison (United States)
Jonathan Celli, Univ. of Massachusetts Boston (United States)
The panel will discuss whether the use of quantitative, spatially resolved PDT dosimetry has an impact on a patient’s clinical outcome. What is the benefit of dosimetry for standardized treatment protocols versus its use in personalized PDT treatment planning?
Clinical translation of PDT, whether investigator-initiated or sponsored by industry, still relies heavily on standardized treatment protocols adjusted to the size and location of the malignancy. Given that light (photon) delivery rate and total dose are under the control of the clinician, the PDT dose can be modulated within limits given by the tissue’s optical properties; knowledge of the PDT efficacy determining parameters should yield improved outcomes. When and how can this information be obtained, and under what conditions is including this information in the clinical praxis advantageous for the patient? The aim is to present and discuss current dosimetry approaches, what dosimetry concepts are best for predicting PDT outcomes, and their suitability for their clinical implementation.
This panel is part of the Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXIII conference.
MENU: Coffee, decaf, and tea will be available outside the presentation room.
SETUP: Classroom and theater style seating.
Lothar Lilge, Univ. Health Network (Canada)
Panelists:
Dominic Robinson, Erasmus MC (Netherlands)
Brian Pogue, Univ. of Wisconsin-Madison (United States)
Jonathan Celli, Univ. of Massachusetts Boston (United States)
The panel will discuss whether the use of quantitative, spatially resolved PDT dosimetry has an impact on a patient’s clinical outcome. What is the benefit of dosimetry for standardized treatment protocols versus its use in personalized PDT treatment planning?
Clinical translation of PDT, whether investigator-initiated or sponsored by industry, still relies heavily on standardized treatment protocols adjusted to the size and location of the malignancy. Given that light (photon) delivery rate and total dose are under the control of the clinician, the PDT dose can be modulated within limits given by the tissue’s optical properties; knowledge of the PDT efficacy determining parameters should yield improved outcomes. When and how can this information be obtained, and under what conditions is including this information in the clinical praxis advantageous for the patient? The aim is to present and discuss current dosimetry approaches, what dosimetry concepts are best for predicting PDT outcomes, and their suitability for their clinical implementation.
This panel is part of the Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXIII conference.
Event Details
FORMAT: Panel discussion followed by audience Q&A.MENU: Coffee, decaf, and tea will be available outside the presentation room.
SETUP: Classroom and theater style seating.